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An adjunct in the assessment of conditions associated with increased bone turnover, such as paget disease Pinp is considered the most sensitive marker of bone formation and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies This test should not be used as a screening test for osteoporosis in the general population

Pinp is considered the most sensitive marker of bone formation, and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies This test should not be used as a screening test for osteoporosis in the general population. It is recommended that the test be performed at baseline before starting osteoporosis therapy and performed again 3 to 6 months later.

1 as the concentration of this extension propeptide is directly proportional to the amount of new collagen laid down in bone, it can be used to assess bone formation.

Collect all specimens at the same time of day There is a diurnal variation of pinp and values are higher at night Specimen preparation instructions for specimen prep before/after collection and prior to transport It is recommended that the test be performed at baseline before starting osteoporosis therapy and performed agai.

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