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Types of vasculitis there are approximately 20 different disorders that are classified as “vasculitis” Syphilis is one example of vasculitis that can be caused by infection in the blood vessel. “ angiitis ” and “ arteritis ” are both synonyms for vasculitis, literally meaning “inflammation within blood vessels” or “inflammation in arteries.”
The active vasculitis associated with rheumatoid disease occurs in about 1% of this patient population Certain forms of vasculitis that can be due to infection where the microbe directly invades the vessel wall Different types of vasculitis have characteristic (localized) patterns of blood vessel involvement
However, vasculitis is often a systemic illness
Thus, patients with vasculitis generally feel sick They often have fevers, weight loss, fatigue, a rapid pulse, and diffuse aches and pains that are difficult to pinpoint. Granulomatosis with polyangiitis is a disease involving granulomatous inflammation, necrosis and vasculitis that most frequently targets the upper respiratory tract, lower respiratory tract, and kidneys Although granulomatosis with polyangiitis can begin at any age, the average age of onset is about 40 years.
The diagnosis of vasculitis usually requires a biopsy of an involved organ (skin, kidney, lung, nerve, temporal artery) This allows us to ‘see’ the vasculitis by looking under a microscope to see the inflammatory immune cells in the wall of the blood vessel. Other forms of vasculitis (e.g., buerger’s disease, a disease strongly associated with cigarette smoking) resolve with institution of the definitive treatment Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of hsp
The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed
However, all four elements of this tetrad are not required for diagnosis. Takayasu’s arteritis is a chronic inflammatory condition that affects the largest blood vessel in the body (the aorta) and its branches Thus, the complications of takayasu’s arise directly or indirectly from damage to these blood vessels The vasculitides are classified according to the size of blood vessel involved.
Causes of vasculitis there are many different types of vasculitis, some with different causes than others
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